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CS-W001157 4
Total: USD 88.00

2-((Tert-butyldimethylsilyl)oxy)acetic acid

  • CAS No. 105459-05-0

  • Cat. No. CS-0272381
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-((Tert-butyldimethylsilyl)oxy)acetic acid|CS-0272381

Structure of 105459-05-0

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General Information

  • CAS No. 105459-05-0
  • Cat. No. CS-0272381
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₈O₃Si
  • Molecular Weight 190.31
  • Synonym(s) 2-(Tert-butyldimethylsilyloxy)acetic acid
  • SMILES CC(C)(C)[Si](C)(C)OCC(=O)O

Synthesis

  • Route1
    • Ethyl 2-((tert-butyldimethylsilyl)oxy)acetate|CS-0119884
      67226-78-2
    • ~90%
    • 2-((Tert-butyldimethylsilyl)oxy)acetic acid|CS-0272381
      105459-05-0

    References

    • Liu, Lian Jin; Yoo, Jin Cheol; Hong, Joon Hee Nucleosides, Nucleotides and Nucleic Acids, 2008 , vol. 27, # 10-11 p. 1186 - 1196
  • Route2
    • Benzyl 2-((tert-butyldimethylsilyl)oxy)acetate|CS-0570798
      115118-86-0
    • ~96%
    • 2-((Tert-butyldimethylsilyl)oxy)acetic acid|CS-0272381
      105459-05-0

    References

    • Barrish, Joel C.; Lee, Hsi Lin; Mitt, Toomas; Pizzolato, Giacomo; Baggiolini, Enrico G; Uskokovic, Milan R Journal of Organic Chemistry, 1988 , vol. 53, # 18 p. 4282 - 4295
  • Route3
    • null|null
      114790-31-7
    • ~88%
    • 2-((Tert-butyldimethylsilyl)oxy)acetic acid|CS-0272381
      105459-05-0

    References

    • Bischofberger, Norbert; Waldmann, Herbert; Saito, Tohru; Simon, Ethan S.; Lees, Watson; et al. Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3457 - 3465

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   2.0928
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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