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Methyl 3,6-dihydro-2H-pyran-4-carboxylate

  • CAS No. 105772-14-3

  • Cat. No. CS-0049135
  • Purity≥96%
  • MDL No.MFCD11706987

*For research and further manufacturing use only, not for direct human use.

Methyl 3,6-dihydro-2H-pyran-4-carboxylate|CS-0049135

Structure of 105772-14-3

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General Information

  • CAS No. 105772-14-3
  • Cat. No. CS-0049135
  • Purity ≥96%
  • MDL No. MFCD11706987
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀O₃
  • Molecular Weight 142.15
  • Synonym(s) 3,6-Dihydro-2H-pyran-4-carboxylic acid methyl ester
  • SMILES COC(=O)C1=CCOCC1

Description

Methyl 3,6-dihydro-2H-pyran-4-carboxylate is a bench-stable, moisture-tolerant heterocyclic ester featuring a protected diol scaffold. This versatile building block integrates readily into synthetic sequences requiring controlled reactivity and selective functionalization. Its electron-rich pyran ring facilitates regioselective transformations, enabling streamlined access to complex oxygenated architectures in natural product synthesis and medicinal chemistry applications.

Application

Methyl 3,6-dihydro-2H-pyran-4-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to oxygen-containing heterocycles and functionalized intermediates. Its stable dihydropyran core exhibits excellent compatibility with standard coupling reactions, while the ester group facilitates selective transformations under mild conditions. The molecule functions as a key scaffold for carbohydrate mimetics and bioactive compound synthesis, offering predictable reactivity and straightforward purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   0.5061
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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