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CS-W001157 4
Total: USD 88.00

1-(5-Methylfuran-2-yl)propan-1-one

  • CAS No. 10599-69-6

  • Cat. No. CS-0132447
  • Purity≥95%
  • MDL No.MFCD00053142

*For research and further manufacturing use only, not for direct human use.

1-(5-Methylfuran-2-yl)propan-1-one|CS-0132447

Structure of 10599-69-6

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General Information

  • CAS No. 10599-69-6
  • Cat. No. CS-0132447
  • Purity ≥95%
  • MDL No. MFCD00053142
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀O₂
  • Molecular Weight 138.16
  • Synonym(s) 2-methyl-5-propionyl-furan
  • SMILES CCC(C1=CC=C(C)O1)=O

Description

This α,β-unsaturated ketone features a 5-methylfuran ring linked to a propanone side chain, delivering enhanced reactivity in cross-coupling and cyclization processes. The furan moiety provides electron-rich character, while the carbonyl group enables nucleophilic attack under mild conditions. Bench-stable and moisture-tolerant, it integrates efficiently into complex molecular architectures.

Application

1-(5-Methylfuran-2-yl)propan-1-one serves as a versatile building block for heterocyclic synthesis, particularly in the construction of furan-based pharmacophores. Its α,β-unsaturated ketone functionality enables efficient Michael additions and aldol-type reactions. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P261-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   30.21
  • LogP   2.18072
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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