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Structure of 1060810-41-4
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2-Bromo-6-methoxynicotinaldehyde features a bromine substituent and methoxy group positioned ortho and para to the aldehyde functionality, respectively, enabling selective coupling reactions. This electron-deficient heteroaryl aldehyde integrates readily into synthetic scaffolds requiring halogen-directed functionalization or metal-catalyzed cross-coupling processes under standard conditions.
2-Bromo-6-methoxynicotinaldehyde serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling direct functionalization at the C2 position via palladium-catalyzed cross-coupling reactions. Its aldehyde functionality facilitates efficient imine formation and reductive amination, while the methoxy group provides orthogonal reactivity and improved solubility. The molecule exhibits excellent bench stability and compatibility with standard synthetic workflows, making it ideal for constructing complex pyridine-based scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: