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Structure of 106429-29-2
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1H-Benzimidazol-5-ylmethanol features a benzimidazole core with a pendant hydroxymethyl group, offering a versatile scaffold for medicinal chemistry and functional material synthesis. The hydroxymethyl moiety enables straightforward derivatization via oxidation or etherification, while the aromatic heterocycle provides robust planarity and hydrogen-bonding capacity. This compound exhibits favorable solubility in polar solvents and stability under standard bench conditions, facilitating integration into multi-step synthetic sequences.
1H-Benzimidazol-5-ylmethanol serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its benzimidazole core provides robust metabolic stability and favorable pharmacokinetic properties, while the pendant hydroxymethyl group facilitates straightforward derivatization via oxidation, etherification, or coupling reactions. The compound exhibits excellent bench stability and is compatible with standard purification protocols, making it well-suited for high-throughput synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: