Methyl 4-bromo-2-chloronicotinate

Name: Methyl 4-bromo-2-chloronicotinate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1064678-14-3
Cat. No. CS-0112315
Purity≥98%
MDL No.MFCD21364445

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 4-bromo-2-chloronicotinate|CS-0112315

Structure of 1064678-14-3

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Methyl 4-bromo-2-chloronicotinate features a uniquely activated pyridine core bearing bromo and chloro substituents at the 4- and 2-positions, respectively. This electron-deficient heterocycle enables efficient cross-coupling reactions under palladium catalysis. The methyl ester group provides stability and facilitates downstream derivatization. This compound serves as a key intermediate in the synthesis of bioactive nitrogen-containing scaffolds.

Application

Methyl 4-bromo-2-chloronicotinate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogenation pattern. The bromo and chloro substituents facilitate sequential functionalization under orthogonal conditions, while the methyl ester group supports subsequent transformations such as hydrolysis or reduction. Its bench-stable nature and compatibility with standard synthetic workflows make it ideal for constructing complex scaffolds in medicinal chemistry and agrochemical research.

General Information

CAS No. 1064678-14-3
Cat. No. CS-0112315
Purity ≥98%
MDL No. MFCD21364445
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅BrClNO₂
Molecular Weight 250.48
Synonym(s) methyl 4-bromo-2-methylnicotinate
SMILES O=C(C1=C(Br)C=CN=C1Cl)OC

Computational Chemistry Data

TPSA 39.19
LogP 2.2841
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS08,GHS09
Signal Word : Danger	UN#: 3077
Class : 9	Packing Group : Ⅲ
Hazard Statements : H302-H361-H372-H410
Precautionary Statements : P264-P280-P301+P330+P331

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

Methyl 4-bromo-2-chloronicotinate sigmaMethyl 4-bromo-2-chloronicotinate manufacturerMethyl 4-bromo-2-chloronicotinate priceMethyl 4-bromo-2-chloronicotinate structureMethyl 4-bromo-2-chloronicotinate SDSbuy Methyl 4-bromo-2-chloronicotinateMethyl 4-bromo-2-chloronicotinate supplierMethyl 4-bromo-2-chloronicotinate usesMethyl 4-bromo-2-chloronicotinate molecular weightprice of Methyl 4-bromo-2-chloronicotinateMethyl 4-bromo-2-chloronicotinate chemical name formula of Methyl 4-bromo-2-chloronicotinate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 4-bromo-2-chloronicotinate

CAS No. 1064678-14-3

Recommended Products