(1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol

Name: (1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol
Brand: ChemScene
Availability: InStock
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CAS No. 1065100-83-5
Cat. No. CS-0037417
Purity≥98%
MDL No.MFCD11054203

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(1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol|CS-0037417

Structure of 1065100-83-5

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Description

(1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol features a heteroaromatic core with a pendant hydroxymethyl group, enabling direct functionalization in late-stage synthesis. This bench-stable scaffold integrates readily into bioactive molecules, offering enhanced solubility and metabolic stability in pharmaceutical development workflows.

Application

(1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pharmacologically relevant scaffolds. The pendant alcohol functions as a handle for derivatization via oxidation, protection, or coupling reactions, while the fused pyrrolopyridine core exhibits favorable stability and compatibility with common reaction conditions. Its utility in medicinal chemistry workflows is supported by predictable reactivity and straightforward purification.

General Information

CAS No. 1065100-83-5
Cat. No. CS-0037417
Purity ≥98%
MDL No. MFCD11054203
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈N₂O
Molecular Weight 148.16
Synonym(s) 3-Hydroxymethyl-7-azaindole
SMILES C1=CC2=C(N=C1)NC=C2CO

Computational Chemistry Data

TPSA 48.91
LogP 1.0552
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Key Words

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(1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol

CAS No. 1065100-83-5

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