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Structure of 1065483-60-4
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2-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-imidazole serves as a stable, moisture-tolerant imidazole derivative featuring a protected hydroxyl group. This bench-stable reagent integrates readily into synthetic sequences requiring selective C–H functionalization or heterocycle coupling, delivering high yields under mild conditions.
2-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-imidazole serves as a stable, bench-accessible imidazole building block enabling direct C2 functionalization in heterocyclic synthesis. The tetrahydro-2H-pyran-2-yl protecting group offers excellent stability under standard reaction conditions and can be readily removed via mild acidolysis, facilitating downstream derivatization. This compound functions effectively in palladium-catalyzed cross-coupling reactions and provides orthogonal reactivity for late-stage modification in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: