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CS-W001157 4
Total: USD 88.00

Methyl 6-(3-(adamantan-1-yl)-4-methoxyphenyl)-2-naphthoate

  • CAS No. 106685-41-0

  • Cat. No. CS-0150365
  • Purity≥95%
  • MDL No.MFCD08063923

*For research and further manufacturing use only, not for direct human use.

Methyl 6-(3-(adamantan-1-yl)-4-methoxyphenyl)-2-naphthoate|CS-0150365

Structure of 106685-41-0

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General Information

  • CAS No. 106685-41-0
  • Cat. No. CS-0150365
  • Purity ≥95%
  • MDL No. MFCD08063923
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₉H₃₀O₃
  • Molecular Weight 426.55
  • Synonym(s) Metyl 6-[3-(1-Adamantyl)-4-Methoxy Phenyl]-2-Naphthoate
  • SMILES COC1=CC=C(C=C1C23CC4CC(CC(C4)C2)C3)C5=CC6=CC=C(C=C6C=C5)C(=O)OC

Synthesis

  • Route1
    • Methyl 6-bromo-2-naphthoate Adapalene Impurity|CS-0228706
      33626-98-1
    • In-stock
      1-(5-Bromo-2-methoxyphenyl)adamantane|CS-W009894
      104224-63-7
    • ~88%
    • In-stock
      Methyl 6-(3-(adamantan-1-yl)-4-methoxyphenyl)-2-naphthoate|CS-0150365
      106685-41-0

    References

    • Liu, Zhichang; Xiang, Jiannan Organic Process Research and Development, 2006 , vol. 10, # 2 p. 285 - 288
  • Route2
    • Methyl 6-bromo-2-naphthoate Adapalene Impurity|CS-0228706
      33626-98-1
    • In-stock
      1-(5-Bromo-2-methoxyphenyl)adamantane|CS-W009894
      104224-63-7
    • ~91%
    • 1,1'-(4,4'-Dimethoxy-[1,1'-biphenyl]-3,3'-diyl)bis(adamantane) Adapalene Impurity|CS-0531400
      932033-57-3
    • In-stock
      Methyl 6-(3-(adamantan-1-yl)-4-methoxyphenyl)-2-naphthoate|CS-0150365
      106685-41-0

    References

    • Puig Serrano, Jordi Patent: US2009/131713 A1, 2009 ; Location in patent: Page/Page column 3; 5 ;
  • Route3
    • Adapalene Impurity 7|CS-1658025
      106685-43-2
    • null|null
      74-88-4
    • ~79%
    • In-stock
      Methyl 6-(3-(adamantan-1-yl)-4-methoxyphenyl)-2-naphthoate|CS-0150365
      106685-41-0

    References

    • Cincinelli, Raffaella; Musso, Loana; Giannini, Giuseppe; Zuco, Valentina; De Cesare, Michelandrea; Zunino, Franco; Dallavalle, Sabrina European Journal of Medicinal Chemistry, 2014 , vol. 79, p. 251 - 259

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335-H361
Precautionary Statements : P201-P202-P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P308+P313-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   6.7698
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   4

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