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CS-W001157 4
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6-oxo-1,6-dihydropyridine-3-carbaldehyde

  • CAS No. 106984-91-2

  • Cat. No. CS-W019709
  • Purity≥98%
  • MDL No.MFCD08689585
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

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*For research and further manufacturing use only, not for direct human use.

6-oxo-1,6-dihydropyridine-3-carbaldehyde|CS-W019709

Structure of 106984-91-2

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Description

6-Oxo-1,6-dihydropyridine-3-carbaldehyde features a reactive α,β-unsaturated carbonyl system that enables direct conjugate addition reactions. This electron-deficient heterocycle integrates readily into synthetic scaffolds requiring pyridine-based core functionality with pendant aldehyde handles for downstream derivatization under mild conditions.

Application

6-Oxo-1,6-dihydropyridine-3-carbaldehyde serves as a versatile scaffold for heterocyclic synthesis, enabling efficient access to pyridine-based pharmacophores. Its conjugated enone-aldehyde system facilitates nucleophilic additions, Michael reactions, and condensation processes under mild conditions. The molecule exhibits good bench stability and compatibility with common protecting groups, making it a practical building block for medicinal chemistry campaigns targeting kinase inhibitors and CNS agents.

General Information

  • CAS No. 106984-91-2
  • Cat. No. CS-W019709
  • Purity ≥98%
  • MDL No. MFCD08689585
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅NO₂
  • Molecular Weight 123.11
  • Synonym(s) 6-Hydroxynicotinaldehyde
  • SMILES O=CC(C=C1)=CNC1=O

Computational Chemistry Data

  • TPSA   49.93
  • LogP   0.1874
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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