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1,1,1,3,3,5,5,7,7,9,9,11,11,11-Tetradecamethylhexasiloxane

  • CAS No. 107-52-8

  • Cat. No. CS-B1763
  • Molecule weight458.99
  • Purity≥97%
  • MDL No.MFCD08275354

*For research and further manufacturing use only, not for direct human use.

1,1,1,3,3,5,5,7,7,9,9,11,11,11-Tetradecamethylhexasiloxane|CS-B1763

Structure of 107-52-8

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General Information

  • CAS No. 107-52-8
  • Cat. No. CS-B1763
  • Purity ≥97%
  • MDL No. MFCD08275354
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₄₂O₅Si₆
  • Molecular Weight 458.99
  • Synonym(s) Tetradecamethylhexasiloxane
  • SMILES C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C

Description

This tetradecamethylhexasiloxane features a linear siloxane backbone with bulky methyl groups densely distributed along the chain, conferring exceptional thermal stability and low surface energy. The steric shielding from the methyl substituents minimizes intermolecular interactions, enabling facile handling and compatibility in high-performance silicone applications.

Application

1,1,1,3,3,5,5,7,7,9,9,11,11,11-Tetradecamethylhexasiloxane serves as a stable, low-viscosity silicon-based reagent that facilitates efficient silylation of alcohols and amines. Its high steric bulk enhances functional group tolerance and simplifies purification by minimizing side reactions. This compound functions effectively in protective group strategies and acts as a robust silane source in cross-coupling and hydrosilylation processes, offering reliable performance across diverse synthetic workflows.

Synthesis

  • Route1

    References

    • Gmelin Handbook: Si: MVol.C, 103, page 282 - 285
  • Route2
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      1825-62-3
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      78-62-6
    • ~%
    • In-stock
      1,1,1,3,3,5,5,7,7,9,9,11,11,11-Tetradecamethylhexasiloxane|CS-B1763
      107-52-8

    References

    • Corning Glass Works Patent: US2441098 , 1946 ; Full Text Show Details Corning Glass Works Patent: US2457677 , 1943 ; Full Text Show Details Hunter et al. Journal of the American Chemical Society, 1946 , vol. 68, p. 2289
  • Route3

    References

    • Patnode, W. I.; Wilcock, D. F. Journal of the American Chemical Society, 1946 , vol. 68, p. 358 - 363 Full Text View citing articles Show Details Gmelin Handbook: Si: MVol.C, 103, page 282 - 285

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   46.15
  • LogP   5.5464
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   10

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