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Structure of 1071433-05-0
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1-Methyl-1H-indazole-4-carboxylic acid features a rigid, electron-deficient indazole core paired with a methylated nitrogen and a carboxylic acid group at the 4-position. This combination enables direct integration into bioactive scaffolds, particularly in kinase inhibitors and pharmaceutical intermediates, where its polarity and hydrogen-bonding capacity enhance target engagement. The compound exhibits bench-stable handling characteristics under standard conditions.
1-Methyl-1H-indazole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to indazole-based scaffolds through standard amide coupling and decarboxylation protocols. Its carboxylic acid functionality exhibits excellent compatibility with common coupling reagents, while the methylated indazole core provides enhanced metabolic stability and favorable solubility profiles for downstream applications in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: