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Structure of 1071929-08-2
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This thiophene derivative features a 5-iodo-2-methylbenzoyl group and a 4-fluorophenyl substituent, enabling efficient cross-coupling reactions in synthetic chemistry. The electron-deficient thiophene core enhances reactivity in palladium-catalyzed transformations, while the iodine handle provides high functionalization potential. Bench-stable under standard conditions, it serves as a modular scaffold for advanced molecular architectures in medicinal chemistry and materials science.
2-(5-Iodo-2-methylbenzoyl)-5-(4-fluorophenyl)thiophene serves as a versatile building block in cross-coupling chemistry, enabling efficient access to biaryl and heteroaryl scaffolds. The iodide functionality facilitates reliable Suzuki, Stille, or Negishi coupling reactions under standard conditions, while the methyl-substituted benzoyl and fluorophenyl groups provide enhanced stability and favorable electronic properties. Its bench-stable nature and compatibility with diverse reaction environments make it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: