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Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(1-Aziridinyl)ethanol

  • CAS No. 1072-52-2

  • Cat. No. CS-W023058
  • Molecule weight87.12
  • Purity≥95%
  • MDL No.MFCD00005119

*For research and further manufacturing use only, not for direct human use.

2-(1-Aziridinyl)ethanol|CS-W023058

Structure of 1072-52-2

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General Information

  • CAS No. 1072-52-2
  • Cat. No. CS-W023058
  • Purity ≥95%
  • MDL No. MFCD00005119
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉NO
  • Molecular Weight 87.12
  • Synonym(s) 2-aziridin-1-ylethanol
  • SMILES OCCN1CC1

Description

2-(1-Aziridinyl)ethanol features a strained three-membered aziridine ring linked to an ethanolic side chain, enabling efficient nucleophilic ring-opening reactions. This bifunctional scaffold integrates readily into bioconjugation workflows and synthetic intermediates requiring reactive heterocyclic moieties under mild conditions.

Application

2-(1-Aziridinyl)ethanol serves as a versatile building block in synthetic organic chemistry, enabling efficient access to nitrogen-containing heterocycles and bioactive scaffolds. Its reactive aziridine ring facilitates regioselective ring-opening reactions with nucleophiles, while the pendant hydroxyl group offers a handle for derivatization or protection. The compound exhibits good bench stability and is compatible with standard functional group transformations, making it a practical reagent for medicinal chemistry and process development workflows.

Synthesis

  • Route1
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      141-43-5
    • ~%
    • null|null
      151-56-4
    • In-stock
      2-(1-Aziridinyl)ethanol|CS-W023058
      1072-52-2
    • Pyrazine, ≥99%|CS-1268366
      290-37-9

    References

    • Research on Chemical Intermediates, , vol. 38, # 8 p. 1743 - 1750
  • Route2
    • null|null
      75-21-8
    • null|null
      151-56-4
    • ~%
    • In-stock
      2-(1-Aziridinyl)ethanol|CS-W023058
      1072-52-2

    References

    • US2475068 , ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   23.24
  • LogP   -0.7057
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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