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Structure of 107224-21-5
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5-Bromo-6-fluoroquinoline is a halogenated quinoline derivative featuring complementary electrophilic and nucleophilic sites. This electron-deficient heterocycle enables efficient coupling reactions under mild conditions, serving as a key scaffold in medicinal chemistry and materials science applications.
5-Bromo-6-fluoroquinoline serves as a versatile building block in medicinal chemistry and materials science, enabling direct functionalization at both the 5- and 6-positions. Its halogenated quinoline core facilitates palladium-catalyzed cross-coupling reactions, including Suzuki, Stille, and Negishi couplings, with high efficiency and selectivity. The molecule exhibits excellent bench stability, ease of purification, and compatibility with diverse protecting groups, making it well-suited for iterative synthesis of complex heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: