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Structure of 1075-12-3
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7-Fluoroisoquinoline is a bench-stable, electron-deficient heterocycle featuring a fluorine atom at the 7-position, enhancing its reactivity in cross-coupling and electrophilic substitution. This aromatic scaffold integrates readily into pharmaceutical intermediates and functional materials, offering improved metabolic stability and tailored electronic properties for advanced synthetic applications.
7-Fluoroisoquinoline serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C-1 and C-3 positions via palladium-catalyzed cross-coupling. Its electron-deficient aromatic core enhances reactivity in nucleophilic substitution and transition-metal-mediated transformations. The fluorine substituent improves metabolic stability and modulates electronic properties, making it valuable for constructing bioactive heterocycles. Bench-stable and compatible with standard purification methods, it functions reliably in multi-step syntheses of pharmaceutical candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: