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Structure of 1075-25-8
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This indole derivative features a hydroxymethyl group at the 5-position, offering enhanced solubility and reactivity in synthetic transformations. The scaffold integrates readily into bioactive molecule frameworks, serving as a key intermediate for pharmaceutical and agrochemical applications under standard conditions.
(1H-Indol-5-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient functionalization at the indole C5 position. Its benzylic alcohol functionality facilitates oxidation to the aldehyde or carboxylic acid, and it participates reliably in coupling reactions, including Mitsunobu transformations and Suzuki-Miyaura cross-couplings. The compound exhibits good bench stability and is compatible with standard purification methods, making it a practical reagent for synthesizing substituted indoles and heterocyclic scaffolds relevant to drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: