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Structure of 1077-58-3
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2-(tert-Butyl)benzoic acid features a sterically hindered tert-butyl group ortho to the carboxylic acid, enhancing its metabolic stability and solubility in organic media. This structural arrangement promotes favorable handling characteristics and enables efficient incorporation into pharmaceutical intermediates and bioactive molecule scaffolds.
2-(tert-Butyl)benzoic acid serves as a versatile building block in medicinal chemistry and materials science, offering enhanced lipophilicity and steric bulk due to the tert-butyl group. Its carboxylic acid functionality enables direct conversion to acyl chlorides, amides, or esters under standard conditions. The molecule exhibits good bench stability and facilitates efficient purification via recrystallization or chromatography, making it well-suited for iterative synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: