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CS-W001157 4
Total: USD 88.00

Famotidine impurity 8

  • CAS No. 107880-74-0

  • Cat. No. CS-0531738
  • Purity≥96%
  • MDL No.MFCD06208403

*For research and further manufacturing use only, not for direct human use.

Famotidine impurity 8|CS-0531738

Structure of 107880-74-0

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General Information

  • CAS No. 107880-74-0
  • Cat. No. CS-0531738
  • Purity ≥96%
  • MDL No. MFCD06208403
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂N₄O₂S₂
  • Molecular Weight 260.33
  • Synonym(s) Famotidine propionic acid
  • SMILES O=C(O)CCSCC=1N=C(SC1)NC(=N)N

Description

1,25-Dihydroxyvitamin D3 is a biologically active form of vitamin D3 in calcium absorption and deposition. It has widespread effects on cellular differentiation and proliferation, and can modulate immune responsiveness, and central nervous system function. Recent studies suggest that 1,25-dihydroxyvitamin D3 acts as a chemopreventive agent against several malignancies including cancers of the prostate and colon and shows synergy with other anticancer compounds.1,25-Dihydroxyvitamin D3 may be used as a certified reference material for the determination of the analyte in biological fluids by liquid chromatography-tandem mass spectrometry.

Synthesis

  • Route1
    • Famotidine solution|CS-1692832
      76824-35-6
    • ~75%
    • Famotidine impurity 8|CS-0531738
      107880-74-0

    References

    • Yanagisawa, Isao; Hirata, Yasufumi; Ishii, Yoshio Journal of Medicinal Chemistry, 1987 , vol. 30, # 10 p. 1787 - 1793
  • Route2
    • Famotidine impurity 11|CS-0815545
      76823-94-4
    • ~%
    • Famotidine impurity 8|CS-0531738
      107880-74-0

    References

    • Journal of Medicinal Chemistry, , vol. 30, # 10 p. 1787 - 1793

Safety Information

Download SDS
GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   112.09
  • LogP   1.15637
  • H_Acceptors   5
  • H_Donors   4
  • Rotatable_Bonds   6

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