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Structure of 1082-19-5
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1,10-Phenanthroline-2-carbonitrile features a rigid aromatic scaffold with a strategically positioned nitrile group at the 2-position, enhancing its electron-withdrawing character. This configuration supports strong chelation in transition metal complexes while improving solubility and stability under standard conditions. The compound serves as a tunable ligand for catalytic systems requiring controlled electronic properties.
1,10-Phenanthroline-2-carbonitrile serves as a versatile ligand in transition metal catalysis, enabling efficient cross-coupling and C–H functionalization reactions. Its ortho-cyanopyridine moiety enhances electronic modulation and chelation strength, improving catalyst stability and turnover. The nitrile group provides a handle for further derivatization, while the rigid phenanthroline scaffold ensures robust coordination to metals such as palladium and copper. This compound exhibits excellent bench stability and is readily purified by recrystallization or column chromatography, making it well-suited for reproducible synthetic workflows in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: