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Structure of 1082040-50-3
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1-Bromo-5-chloro-3-fluoro-2-methylbenzene features a densely functionalized aromatic ring with halogen and methyl substituents positioned for orthogonal reactivity. The bromine site enables palladium-catalyzed cross-coupling, while the chloro and fluoro groups offer complementary handles for selective transformations. This electron-deficient aryl halide demonstrates enhanced stability under standard bench conditions, facilitating integration into complex synthetic sequences.
1-Bromo-5-chloro-3-fluoro-2-methylbenzene serves as a versatile building block for the synthesis of functionalized aromatic scaffolds. The ortho-methyl group enables directed metallation, while the strategically positioned halogens (Br, Cl, F) support sequential cross-coupling reactions. Its bench-stable nature and compatibility with Pd-catalyzed transformations facilitate efficient access to substituted biaryls and heterocycles in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: