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1H-Pyrrolo[3,2-c]pyridine-6-carboxylic acid

  • CAS No. 1082040-99-0

  • Cat. No. CS-0052488
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1H-Pyrrolo[3,2-c]pyridine-6-carboxylic acid|CS-0052488

Structure of 1082040-99-0

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General Information

  • CAS No. 1082040-99-0
  • Cat. No. CS-0052488
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O₂
  • Molecular Weight 162.15
  • Synonym(s) 5-Azaindole-6-carboxylic acid
  • SMILES OC(=O)C1=NC=C2C=CNC2=C1

Description

1H-Pyrrolo[3,2-c]pyridine-6-carboxylic acid integrates a fused heterocyclic core with a carboxylic acid handle, enabling direct conjugation in medicinal chemistry. This electron-deficient scaffold supports efficient derivatization under standard conditions, offering robust stability for synthetic applications in drug discovery and materials science.

Application

1H-Pyrrolo[3,2-c]pyridine-6-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its carboxylic acid functionality enables direct amidation, esterification, or metal complexation, while the fused pyrrolopyridine core provides structural rigidity and π-conjugation. The compound exhibits good bench stability and facilitates efficient derivatization in standard coupling protocols, making it valuable for constructing bioactive scaffolds and functionalized organic semiconductors.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.98
  • LogP   1.2611
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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