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Structure of 1082041-56-2
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5-Nitro-1H-indazol-6-ol features a fused bicyclic core with a nitro group at C5 and a phenolic hydroxyl at C6, creating a polar, electron-deficient scaffold. This arrangement enables direct participation in cross-coupling reactions and facilitates hydrogen bonding in supramolecular systems. The compound exhibits bench-stable behavior under standard conditions and integrates readily into bioactive molecule design.
5-Nitro-1H-indazol-6-ol serves as a versatile building block for bioactive heterocycles, enabling direct functionalization at the C6 position via nucleophilic substitution or metal-catalyzed coupling. Its nitro group enhances electrophilicity for downstream transformations, while the phenolic OH supports derivatization and hydrogen bonding in medicinal chemistry applications. The compound exhibits good bench stability and facilitates purification via recrystallization, making it suitable for scalable synthesis of kinase inhibitors and other pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: