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Structure of 1086381-28-3
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4-Bromo-2-cyclopropylpyridine is a bench-stable heterocyclic building block featuring a bromine atom at the 4-position and a cyclopropyl group at the 2-position of the pyridine ring. This combination delivers enhanced electronic modulation and steric profile, enabling efficient coupling in cross-coupling reactions. The molecule integrates readily into complex scaffolds for medicinal chemistry and materials science applications.
4-Bromo-2-cyclopropylpyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-established halogen reactivity. The cyclopropyl group imparts favorable steric and electronic properties, enhancing metabolic stability in target molecules. Bench-stable and readily purified, it functions effectively in standard Suzuki, Stille, and Negishi couplings, facilitating efficient assembly of complex heterocyclic scaffolds relevant to pharmaceutical discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: