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Structure of 1086385-16-1
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6-Bromo-2-(methylsulfanyl)quinazoline features a bromine substituent at the 6-position and a methylthio group at the 2-position on the quinazoline core. This electron-deficient scaffold enables direct functionalization in cross-coupling reactions, serving as a key building block for kinase inhibitors and advanced pharmaceutical intermediates under standard conditions.
6-Bromo-2-(methylsulfanyl)quinazoline serves as a versatile building block for the synthesis of quinazoline-based pharmaceutical intermediates. The bromine at C6 enables palladium-catalyzed cross-coupling reactions, while the methylthio group at C2 offers orthogonal reactivity and facilitates further functionalization. Its bench-stable nature and compatibility with standard coupling protocols make it well-suited for medicinal chemistry campaigns requiring rapid scaffold diversification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: