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CS-W001157 4
Total: USD 88.00

Boc-L-Pyroglutamic acid methyl ester

  • CAS No. 108963-96-8

  • Cat. No. CS-W003361
  • Molecule weight243.26
  • Purity≥98%
  • MDL No.MFCD06809720

*For research and further manufacturing use only, not for direct human use.

Boc-L-Pyroglutamic acid methyl ester|CS-W003361

Structure of 108963-96-8

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General Information

  • CAS No. 108963-96-8
  • Cat. No. CS-W003361
  • Purity ≥98%
  • MDL No. MFCD06809720
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇NO₅
  • Molecular Weight 243.26
  • Synonym(s) N-tert-Butoxycarbonyl-L-pyroglutamic acid methyl ester; Boc-L-pyroglutamic acid methyl ester
  • SMILES COC(=O)[C@@H]1CCC(=O)N1C(=O)OC(C)(C)C

Description

Cortisone 21-acetate is a prodrug, which has glucocorticoid and mineralocorticoid properties. It is used as a therapeutic option for glucocorticoid replacement.Cortisone 21-acetate has been used to study its effects in metastasis and phagocytic activity.

Synthesis

  • Route1

    References

    • Tetrahedron, , vol. 50, # 21 p. 6221 - 6238
  • Route2

    References

    • WO2010/9014 A2, ; Page/Page column 6 ; WO 2010/009014 A2
  • Route3
    • null|null
      67-56-1
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • ~51%
    • In-stock
      Boc-L-Pyroglutamic acid methyl ester|CS-W003361
      108963-96-8

    References

    • US2007/232806 A1, ; Page/Page column 3 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H317-H319-H411
Precautionary Statements : P261-P264-P272-P273-P280-P302+P352-P363-P391-P501

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Computational Chemistry Data

  • TPSA   72.91
  • LogP   1.0855
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   1

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