5-Chloro-2-methylthiazolo[5,4-b]pyridine

Name: 5-Chloro-2-methylthiazolo[5,4-b]pyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 109202-21-3
Cat. No. CS-0460458
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Chloro-2-methylthiazolo[5,4-b]pyridine|CS-0460458

Structure of 109202-21-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 109202-21-3
Cat. No. CS-0460458
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅ClN₂S
Molecular Weight 184.65
Synonym(s) 2-methyl-6-chloro-7-azabenzothiazole
SMILES ClC1=NC2=C(C=C1)N=C(C)S2

Description

5-Chloro-2-methylthiazolo[5,4-b]pyridine features a fused thiazole-pyridine core with strategic chlorine and methyl substitutions, enabling enhanced reactivity in cross-coupling transformations. This electron-deficient heterocycle serves as a robust scaffold for pharmaceutical intermediates, offering improved stability and solubility under standard conditions.

Application

5-Chloro-2-methylthiazolo[5,4-b]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and process development. Its chlorinated thiazole-pyridine fusion enables direct cross-coupling reactions and nucleophilic substitution, facilitating rapid diversification of API scaffolds. The methyl group provides a handle for further functionalization, while the compound exhibits excellent bench stability and compatibility with standard synthetic workflows.

Synthesis

Route1
- In-stock
  
  62476-56-6
- 926-67-0
- ~%
- In-stock
  
  109202-21-3
References
- Couture, Axel; Grandclaudon, Pierre; Huguerre, Eric Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1765 - 1770

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 25.78
LogP 2.65312
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Key Words

5-Chloro-2-methylthiazolo[5,4-b]pyridine sigma5-Chloro-2-methylthiazolo[5,4-b]pyridine manufacturer5-Chloro-2-methylthiazolo[5,4-b]pyridine price5-Chloro-2-methylthiazolo[5,4-b]pyridine structure5-Chloro-2-methylthiazolo[5,4-b]pyridine SDSbuy 5-Chloro-2-methylthiazolo[5,4-b]pyridine5-Chloro-2-methylthiazolo[5,4-b]pyridine supplier5-Chloro-2-methylthiazolo[5,4-b]pyridine uses5-Chloro-2-methylthiazolo[5,4-b]pyridine molecular weightprice of 5-Chloro-2-methylthiazolo[5,4-b]pyridine5-Chloro-2-methylthiazolo[5,4-b]pyridine chemical name formula of 5-Chloro-2-methylthiazolo[5,4-b]pyridine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Chloro-2-methylthiazolo[5,4-b]pyridine

CAS No. 109202-21-3

Recommended Products