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Structure of 1092400-82-2
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This trifluoromethyl-substituted oxadiazole-linked benzoic acid integrates a polar, electron-deficient heterocycle with a carboxylic acid handle. The 1,2,4-oxadiazole ring enhances metabolic stability and modulates electronic properties, while the para-carboxyl group enables direct conjugation or derivatization in medicinal chemistry campaigns.
3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid serves as a versatile building block for bioactive heterocycles, enabling efficient access to pharmacologically relevant scaffolds. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the oxadiazole core provides a rigid, polarized linkage ideal for hydrogen bonding and target engagement. This compound facilitates direct coupling reactions with amines or alcohols under standard conditions, offering high functional group tolerance and excellent bench stability—ideal for parallel synthesis and medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: