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Structure of 1105662-87-0
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tert-Butyl 3-(2-methoxy-2-oxoethylidene)azetidine-1-carboxylate features a strained azetidine core stabilized by a methoxy-substituted enol ether motif, enabling selective conjugate additions in complex molecule synthesis. The tert-butyl carbamate group offers excellent stability and convenient deprotection under mild acidic conditions. This reagent integrates readily into diverse synthetic sequences requiring nitrogen-containing heterocycles with defined stereochemical control.
tert-Butyl 3-(2-methoxy-2-oxoethylidene)azetidine-1-carboxylate serves as a stable, bench-ready azetidine building block featuring a reactive α,β-unsaturated carbonyl moiety. It enables efficient Michael additions and cycloadditions, facilitating rapid access to functionalized azetidine scaffolds. The tert-butyl ester group provides excellent stability and ease of purification, while the methoxy-substituted enone system offers tunable reactivity for downstream transformations in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: