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Structure of 110764-74-4
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DMT-2'-OMe-Bz-C delivers a protected nucleoside building block featuring a benzoyl group at the 2'-position and a methoxy substitution, enabling selective coupling in oligonucleotide synthesis. This derivative combines enhanced stability with efficient incorporation under standard conditions, supporting streamlined phosphoramidite workflows.
DMT-2'-OMe-Bz-C serves as a key building block for the synthesis of modified oligonucleotides, enabling site-specific incorporation of 2'-O-methyl and benzoyl-protected ribose units. Its robust DMT group ensures efficient purification via reverse-phase chromatography, while the 2'-OMe-Bz moiety provides enhanced nuclease resistance and improved binding affinity. The compound exhibits excellent stability under standard phosphoramidite coupling conditions and facilitates reliable synthesis of complex antisense constructs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: