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Structure of 111773-24-1
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Ethyl 3-bromo-2,2-difluoropropanoate features a trifluoromethyl-like electronic profile due to the geminal difluoro substitution, enabling unique reactivity in fluorinated building block synthesis. The α-bromo ester moiety facilitates nucleophilic displacement and cross-coupling transformations under mild conditions. This bench-stable reagent integrates readily into complex molecular architectures requiring stereocontrolled fluorination or C–C bond formation.
Ethyl 3-bromo-2,2-difluoropropanoate serves as a versatile building block for fluorinated synthetic intermediates, enabling efficient construction of difluoromethyl-containing motifs via nucleophilic substitution or elimination reactions. Its stability under standard bench conditions and compatibility with palladium-catalyzed cross-couplings facilitate the synthesis of complex fluorinated scaffolds relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS02,GHS06
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Signal Word : Danger
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UN#: 3272
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H301-H315-H319-H332-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: