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CS-W001157 4
Total: USD 88.00

PEG2-Dichloride

  • CAS No. 112-26-5

  • Cat. No. CS-0158308
  • Molecule weight187.06
  • Purity≥98%
  • MDL No.MFCD00000976

*For research and further manufacturing use only, not for direct human use.

PEG2-Dichloride|CS-0158308

Structure of 112-26-5

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General Information

  • CAS No. 112-26-5
  • Cat. No. CS-0158308
  • Purity ≥98%
  • MDL No. MFCD00000976
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂Cl₂O₂
  • Molecular Weight 187.06
  • Synonym(s) Triglycol dichloride
  • SMILES ClCCOCCOCCCl

Description

1,2-bis(2-chloroethoxy)ethane was used in the synthesis of 1,1-[1,2-ethanediylbis(oxy-1,2-ethanediyl)]bis[3-methyl-1H-imidazolium-1-yl] chloride.

Application

1,2-Bis(2-chloroethoxy)ethane serves as a versatile bifunctional electrophile in organic synthesis, enabling efficient ether linkage formation and chain extension. Its dual chloroethyl ether functionalities facilitate nucleophilic substitution under mild conditions, offering reliable access to polyether architectures. The compound exhibits good bench stability and ease of purification, making it well-suited for iterative synthetic sequences and the construction of complex molecular scaffolds.

Synthesis

  • Route1

    References

    • Zniber, Rachid; Regragui, Mohamed; Achour, Redouane; Cherkaoul, Omar; Hajji, Ahmed Jalal El; Cherkaoui, Mohammed Zoubair Bulletin des Societes Chimiques Belges, 1996 , vol. 105, # 8 p. 457 - 462
  • Route2
    • PEG3-bis(carbonochloridic acid)|CS-0907649
      17134-17-7
    • ~97%
    • In-stock
      PEG2-Dichloride|CS-0158308
      112-26-5

    References

    • Violleau; Thiebaud; Borredon; Le Gars Synthetic Communications, 2001 , vol. 31, # 3 p. 367 - 373
  • Route3

    References

    • Holmes, Brian T.; Snow, Arthur W. Patent: US2009/187037 A1, 2009 ; Location in patent: Page/Page column 2-3 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H312-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   1.4972
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   7

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