Furo[3,2-b]pyridine-2-carbaldehyde

Name: Furo[3,2-b]pyridine-2-carbaldehyde
Brand: ChemScene
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CAS No. 112372-05-1
Cat. No. CS-0055424
Purity≥97%
MDL No.None

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Furo[3,2-b]pyridine-2-carbaldehyde|CS-0055424

Structure of 112372-05-1

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Description

Furo[3,2-b]pyridine-2-carbaldehyde delivers a rigid, electron-deficient heterocyclic scaffold ideal for transition-metal-catalyzed coupling reactions. The aldehyde group enables direct functionalization, while the fused furan-pyridine core enhances planarity and stability under standard conditions. This structure integrates seamlessly into complex molecular architectures requiring precise spatial control and enhanced reactivity.

Application

Furo[3,2-b]pyridine-2-carbaldehyde serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its fused furan-pyridine core provides enhanced rigidity and electron-deficient character, enabling efficient coupling reactions and functionalization at the aldehyde and pyridine nitrogen. The aldehyde group facilitates nucleophilic additions, imine formation, and downstream derivatization, while the scaffold exhibits good bench stability and compatibility with standard purification methods.

General Information

CAS No. 112372-05-1
Cat. No. CS-0055424
Purity ≥97%
MDL No. None
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₅NO₂
Molecular Weight 147.13
Synonym(s) Furo[3,2-b]pyridine-2-carboxaldehyde (9CI)
SMILES C1=CC2=C(C=C(O2)C=O)N=C1

Computational Chemistry Data

TPSA 43.1
LogP 1.6403
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P261-P280-P304+P340-P405

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Furan compounds

Key Words

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Furo[3,2-b]pyridine-2-carbaldehyde

CAS No. 112372-05-1

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