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Structure of 113451-59-5
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(1S,4S)-(-)-2-Boc-2,5-diazabicyclo[2.2.1]heptane may be used in the preparation of 2-boc-5-(4-nitrophenyl)-2,5-diaza-bicyclo[2.2.1]heptane by reacting with p-nitrobenzene.It may also be used to develop:indazolylpyrazolo[1,5-a]pyrimidine analogs based B-Raf inhibitorsCCR2 antagonists42 nicotinic acetylcholine receptor (nAChR) partial agonistsazabicyclic sulfonamide based 11-hydroxysteroid dehydrogenase type 1 (11-HSD1) inhibitors
(1S,4S)-2-Boc-2,5-diazabicyclo[2.2.1]heptane serves as a conformationally constrained chiral diamine scaffold, enabling stereoselective transformations in asymmetric synthesis. The Boc-protected amine functionality offers stability and orthogonal deprotection, facilitating sequential functionalization. Its rigid bicyclic structure imparts defined spatial orientation, enhancing diastereoselectivity in catalytic reactions and serving as a key building block for bioactive heterocycles and ligand development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: