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Structure of 1135283-10-1
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1-Ethynyl-2-methoxy-4-nitrobenzene features a terminal alkyne group conjugated to an electron-deficient aromatic ring bearing a methoxy and nitro substituent. This combination enables efficient copper-catalyzed coupling reactions under mild conditions, offering enhanced reactivity in click chemistry applications. The molecule exhibits excellent stability and solubility in common organic solvents, facilitating straightforward handling in synthetic workflows.
1-Ethynyl-2-methoxy-4-nitrobenzene serves as a versatile building block in transition-metal-catalyzed coupling reactions, enabling efficient access to conjugated aryl architectures. The ethynyl group facilitates Sonogashira and Glaser-type couplings with high functional group tolerance, while the ortho-methoxy and para-nitro substituents provide electronic modulation and synthetic handle for further derivatization. Its bench-stable nature and straightforward purification support reliable integration into multi-step syntheses of advanced intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: