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CS-W001157 4
Total: USD 88.00

1,3-Di(thiophen-2-yl)propane-1,3-dione

  • CAS No. 1138-14-3

  • Cat. No. CS-0161859
  • Purity≥97%
  • MDL No.MFCD00797223

*For research and further manufacturing use only, not for direct human use.

1,3-Di(thiophen-2-yl)propane-1,3-dione|CS-0161859

Structure of 1138-14-3

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General Information

  • CAS No. 1138-14-3
  • Cat. No. CS-0161859
  • Purity ≥97%
  • MDL No. MFCD00797223
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈O₂S₂
  • Molecular Weight 236.31
  • Synonym(s) di-2-thenoylmethane
  • SMILES O=C(C1=CC=CS1)CC(C2=CC=CS2)=O

Description

1,3-Di(thiophen-2-yl)propane-1,3-dione features a conjugated diketone core flanked by thiophene rings, enabling strong π-stacking and electron delocalization. This structure supports integration into organic semiconductors and donor-acceptor architectures, offering enhanced charge transport properties under ambient conditions.

Application

1,3-Di(thiophen-2-yl)propane-1,3-dione serves as a versatile building block for heterocyclic synthesis, particularly in the construction of thiophene-fused polycycles. Its diketone functionality enables efficient cyclization with hydrazines, amines, and other nucleophiles under mild conditions. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Ishii, Akihiko; Nakayama, Juzo; Kazami, Jun-ichi; Ida, Yutaka; Nakamura, Takao; Hoshino, Masamatsu Journal of Organic Chemistry, 1991 , vol. 56, # 1 p. 78 - 82
  • Route2
    • null|null
      5271-67-0
    • null|null
      75-11-6
    • ~80%
    • In-stock
      1,3-Di(thiophen-2-yl)propane-1,3-dione|CS-0161859
      1138-14-3

    References

    • Matsubara, Seijiro; Yoshino, Hideaki; Yamamoto, Yuhei; Oshima, Koichiro; Matsuoka, Hideki; Matsumoto, Kozo; Ishikawa, Kazuhiko; Matsubara, Eiichiro Journal of Organometallic Chemistry, 2005 , vol. 690, # 24-25 p. 5546 - 5551
  • Route3
    • null|null
      5271-67-0
    • null|null
      31729-70-1
    • ~84%
    • In-stock
      1,3-Di(thiophen-2-yl)propane-1,3-dione|CS-0161859
      1138-14-3

    References

    • Matsubara, Seijiro; Yamamoto, Yuhei; Utimoto, Kiitiro Synlett, 1999 , # 9 p. 1471 - 1473

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   34.14
  • LogP   3.2653
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

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