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Structure of 1138450-30-2
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This boronate moiety integrates a trifluoromethyl group at the pyrazole 3-position, enhancing electron deficiency and metabolic stability. The methyl substitution at the pyrazole 1-position improves solubility and reduces aggregation. This bench-stable reagent facilitates efficient Suzuki-Miyaura coupling under standard conditions, enabling rapid access to fluorinated heterocyclic scaffolds in medicinal chemistry and materials science.
[1-Methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, making it valuable for medicinal chemistry applications. The boronic acid functionality offers excellent bench stability, tolerance to diverse functional groups, and straightforward purification via standard aqueous workup.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: