2-Bromo-5-cyclopropylpyridine

Name: 2-Bromo-5-cyclopropylpyridine
Brand: ChemScene
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CAS No. 1142197-14-5
Cat. No. CS-W019243
Purity≥97%
MDL No.MFCD11869551

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2-Bromo-5-cyclopropylpyridine|CS-W019243

Structure of 1142197-14-5

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Description

2-Bromo-5-cyclopropylpyridine features a cyclopropyl group at the pyridine ring's 5-position, enhancing steric and electronic modulation. This bench-stable heterocycle integrates readily into cross-coupling reactions, serving as a key building block for functionalized pharmaceutical intermediates and agrochemicals.

Application

2-Bromo-5-cyclopropylpyridine serves as a versatile building block in medicinal chemistry and cross-coupling synthesis. The bromine substituent enables reliable Pd-catalyzed transformations such as Suzuki, Stille, and Negishi couplings, while the cyclopropyl group imparts favorable steric and electronic properties. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for constructing complex heterocyclic scaffolds in API development.

General Information

CAS No. 1142197-14-5
Cat. No. CS-W019243
Purity ≥97%
MDL No. MFCD11869551
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈BrN
Molecular Weight 198.06
Synonym(s) None
SMILES BrC1=NC=C(C2CC2)C=C1

Computational Chemistry Data

TPSA 12.89
LogP 2.7215
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Fatty ring compounds Cyclopropane compounds

Key Words

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2-Bromo-5-cyclopropylpyridine

CAS No. 1142197-14-5

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