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Structure of 1142400-61-0
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Tert-butyl 2-(chloromethyl)pyrrolidine-1-carboxylate is a bench-stable, moisture-tolerant building block featuring a reactive chloromethyl group poised for nucleophilic substitution. The tert-butyl ester provides orthogonal protection, enabling selective deprotection under mild acidic conditions. This molecule integrates readily into complex molecular architectures via C–C or C–heteroatom bond formation.
Tert-butyl 2-(chloromethyl)pyrrolidine-1-carboxylate serves as a versatile building block for constructing pyrrolidine-containing scaffolds in medicinal chemistry. The chloromethyl group enables efficient alkylation reactions, while the tert-butyl carbamate protects the amine under standard conditions. This reagent offers excellent bench stability, ease of purification, and compatibility with diverse functional groups, facilitating rapid access to complex heterocycles and API intermediates through well-established synthetic protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: