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Structure of 1146162-54-0
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This pyrazole boronate ester integrates a stable tetramethylborolane handle with a trimethylsilyl-protected hydroxymethyl group, enabling orthogonal functionalization in complex molecule assembly. The combination delivers enhanced stability and selective reactivity under standard coupling conditions.
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazole serves as a robust boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylborolane moiety enables efficient palladium-catalyzed coupling under mild conditions, while the (trimethylsilyl)ethoxymethyl group provides orthogonal protection and enhanced bench stability. This dual functionality facilitates selective deprotection and downstream functionalization in complex molecule synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: