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CS-W001157 4
Total: USD 88.00

1,3-Dimethylpyrazole-4-boronic acid

  • CAS No. 1146616-03-6

  • Cat. No. CS-0044698
  • Purity≥95%
  • MDL No.MFCD18250638
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

1,3-Dimethylpyrazole-4-boronic acid|CS-0044698

Structure of 1146616-03-6

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Description

1,3-Dimethylpyrazole-4-boronic acid features a boronic acid group tethered to a sterically hindered pyrazole scaffold, enabling stable coupling in Suzuki-Miyaura reactions. The electron-rich heterocycle enhances reactivity while maintaining bench-stability and moisture tolerance, simplifying handling in synthetic workflows.

Application

1,3-Dimethylpyrazole-4-boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. Its pyrazole core provides enhanced stability and favorable solubility, while the boronic acid group exhibits high reactivity with aryl and vinyl halides. The methyl substituents improve bench stability and facilitate purification, making it well-suited for iterative synthesis of heterocyclic scaffolds in medicinal chemistry and materials science applications.

General Information

  • CAS No. 1146616-03-6
  • Cat. No. CS-0044698
  • Purity ≥95%
  • MDL No. MFCD18250638
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉BN₂O₂
  • Molecular Weight 139.95
  • Synonym(s) 1,3-Dimethyl-1H-pyrazol-4-ylboronic acid
  • SMILES OB(C1=CN(C)N=C1C)O

Computational Chemistry Data

  • TPSA   58.28
  • LogP   -1.59168
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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