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Structure of 1146637-10-6
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5-Bromo-2,7-dimethyl-2H-indazole is a sterically hindered heterocycle featuring a bromine substituent and two methyl groups at key positions, enabling selective functionalization. This electron-deficient scaffold integrates readily into cross-coupling reactions, offering robust stability under standard conditions for medicinal chemistry applications.
5-Bromo-2,7-dimethyl-2H-indazole serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its bromine atom enables palladium-catalyzed cross-coupling reactions, while the methyl groups provide steric and electronic modulation. The indazole core offers enhanced metabolic stability and hydrogen-bonding capacity, making it valuable in medicinal chemistry campaigns. The compound exhibits excellent bench stability and facilitates straightforward purification via crystallization or flash chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: