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CS-W001157 4
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2-(Tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole

  • CAS No. 1146955-35-2

  • Cat. No. CS-M0484
  • Purity≥95%
  • MDL No.MFCD22124621

*For research and further manufacturing use only, not for direct human use.

2-(Tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole|CS-M0484

Structure of 1146955-35-2

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General Information

  • CAS No. 1146955-35-2
  • Cat. No. CS-M0484
  • Purity ≥95%
  • MDL No. MFCD22124621
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₅BN₂O₃
  • Molecular Weight 328.21
  • Synonym(s) 2-(oxan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole
  • SMILES CC1(C)OB(OC(C)1C)C2=CC=CC3=NN(C4OCCCC4)C=C23

Synthesis

  • Route1
    • null|null
      110-87-2
    • In-stock
      4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole|CS-W009185
      885618-33-7
    • ~85%
    • In-stock
      2-(Tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole|CS-M0484
      1146955-35-2

    References

    • SPHAERA PHARMA PVT. LTD.; DUGAR, Sundeep; MAHAJAN, Dinesh; HOLLINGER PETER, Frank; SHARMA, Amit; TRIPATHI, Vinayak; KUILA, Bilash Patent: WO2014/16849 A2, 2014 ; Location in patent: Page/Page column 113 ;
  • Route2

    References

    • Tian, Qingping; Cheng, Zhigang; Yajima, Herbert M.; Savage, Scott J.; Green, Keena L.; Humphries, Theresa; Reynolds, Mark E.; Babu, Srinivasan; Gosselin, Francis; Askin, David; Kurimoto, Isao; Hirata, Norihiko; Iwasaki, Mitsuhiro; Shimasaki, Yasuharu; Miki, Takashi Organic Process Research and Development, 2013 , vol. 17, # 1 p. 97 - 107
  • Route3

    References

    • GENENTECH, INC.; SUMITOMO CHEMICAL COMPANY, LIMITED Patent: US2012/123122 A1, 2012 ; Location in patent: Page/Page column 12 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   45.51
  • LogP   3.0346
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   2

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