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Structure of 1150114-51-4
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This boronic acid features a difluorinated aromatic ring paired with a hydroxyl and boronic acid group, enabling robust coupling in Suzuki-Miyaura reactions. The ortho-hydroxyl facilitates chelation, enhancing stability and reactivity under standard conditions.
(3,5-Difluoro-2-hydroxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biologically relevant aryl scaffolds. The ortho-hydroxyl group enhances solubility and facilitates chelation-assisted coupling, while the difluoro substitution pattern provides metabolic stability and modulates electronic properties. Bench-stable under ambient conditions, it exhibits excellent functional group tolerance and simplifies purification due to its crystalline nature.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: