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Structure of 1150271-61-6
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Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzoate features a boronate ester group flanked by a trifluoromethyl substituent and an ester moiety. This combination enables efficient coupling in Suzuki-Miyaura reactions, offering enhanced stability and compatibility with diverse reaction conditions.
Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzoate serves as a versatile boronate building block in palladium-catalyzed cross-coupling reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the tetramethyl-substituted dioxaborolane ensures excellent bench stability and functional group tolerance. The methyl ester enables downstream derivatization, making this compound ideal for constructing complex heterocyclic scaffolds and drug-like molecules in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: