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Structure of 1150566-27-0
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Ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate is a bench-stable heterocyclic ester featuring a chlorine atom at the 6-position of an imidazo[1,2-b]pyridazine core. This electron-deficient scaffold integrates readily into medicinal chemistry campaigns, enabling direct coupling or functionalization in late-stage diversification. Its moisture-tolerant nature simplifies handling under standard conditions.
Ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate serves as a versatile building block for constructing imidazopyridazine scaffolds in medicinal chemistry. The chlorine at the C6 position enables palladium-catalyzed cross-coupling reactions with diverse nucleophiles, facilitating rapid diversification. Its ethyl ester group supports subsequent transformations, including hydrolysis and amidation. The compound exhibits good bench stability and is readily purified by flash chromatography, making it well-suited for high-throughput synthesis and API precursor development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: