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Structure of 1150617-92-7
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2-Chloro-5,6-dihydro-7H-cyclopenta[b]pyridin-7-one is a heterocyclic scaffold featuring a chlorine substituent at the 2-position and a ketone functionality at C7. This electron-deficient core integrates readily into medicinal chemistry campaigns, offering a rigid, planar framework for probing target engagement in kinase and GPCR modulators.
2-Chloro-5,6-dihydro-7H-cyclopenta[b]pyridin-7-one serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted pyridine and fused ring systems. Its electrophilic chlorine at the C2 position facilitates nucleophilic substitution under mild conditions, while the enone functionality supports conjugate addition and cyclization reactions. The scaffold exhibits good bench stability and compatibility with common protecting groups, making it suitable for iterative synthetic sequences in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: