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*For research and further manufacturing use only, not for direct human use.
Structure of 115088-06-7
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SPDB is a cleavable, maleimide-functionalized crosslinker designed for site-specific conjugation of biomolecules. Featuring a stable thioether linkage and a labile disulfide bond, it enables efficient bioconjugation under physiological conditions while facilitating controlled release in reducing environments. This property makes SPDB ideal for antibody-drug conjugate development and targeted delivery systems.
SPDB serves as a reliable, bench-stable sulfonamide-based crosslinker for protein conjugation and bioconjugate synthesis. Its reactive sulfonyl chloride group enables efficient coupling with primary amines under mild conditions, offering high functional group tolerance and straightforward purification. Widely used in antibody-drug conjugate (ADC) development and chemical biology applications, SPDB facilitates site-specific modification with minimal side reactions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: