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Structure of 1151802-22-0
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1-Cyclopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole features a boronate ester group that enables efficient Suzuki-Miyaura cross-coupling reactions. The cyclopropyl substituent imparts structural rigidity and favorable lipophilicity, enhancing metabolic stability in bioactive molecule synthesis. This bench-stable reagent integrates seamlessly into complex molecular architectures under standard conditions.
1-Cyclopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a robust boronate building block for Suzuki-Miyaura cross-coupling reactions. The cyclopropylpyrazole core provides metabolic stability and favorable physicochemical properties, while the pinacol boronate moiety enables efficient coupling under mild conditions. Bench-stable and compatible with diverse functional groups, it facilitates rapid access to substituted pyrazole scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: