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CS-W001157 4
Total: USD 88.00

1-(Pyridin-4-yl)-1H-pyrazole-4-carboxylic acid

  • CAS No. 1155066-46-8

  • Cat. No. CS-0441277
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD12134529

*For research and further manufacturing use only, not for direct human use.

1-(Pyridin-4-yl)-1H-pyrazole-4-carboxylic acid|CS-0441277

Structure of 1155066-46-8

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General Information

  • CAS No. 1155066-46-8
  • Cat. No. CS-0441277
  • Purity ≥97%
  • MDL No. MFCD12134529
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇N₃O₂
  • Molecular Weight None
  • Synonym(s) None
  • SMILES C1=C(C=CN=C1)N2C=C(C=N2)C(=O)O

Description

This pyrazole-carboxylic acid integrates a pyridyl moiety for enhanced solubility and coordination potential, delivering a rigid, electron-deficient scaffold ideal for medicinal chemistry applications. The para-substituted pyridine enables efficient coupling reactions under standard conditions.

Application

1-(Pyridin-4-yl)-1H-pyrazole-4-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its pyridyl and carboxylic acid functionalities enable direct conjugation in Suzuki-Miyaura couplings, amide formations, and metal coordination. The compound exhibits excellent bench stability and facilitates purification via standard recrystallization or chromatography, making it well-suited for high-throughput synthesis and API intermediate development.

Safety Information

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Computational Chemistry Data

  • TPSA   68.01
  • LogP   0.9655
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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